General Guidelines cont'd - doe-hdbk-1106-97

DOE-HDBK-1106-97

7. Class B and C carcinogens should be properly labeled and stored with their chemical

family.

8. Store Class A carcinogens in the glovebox or another regulated area.

Note: EPA carcinogen designations are as follows:

EPA-A Human Carcinogen: sufficient evidence from epidemiologic studies to

support a casual association between exposure and cancer.

EPA-B Probable Human Carcinogen: weight of evidence of human carcinogenicity

based on epidemiologic studies is limited; agents for which weight of evidence of

carcinogenicity based on animal studies is sufficient. Two subgroups: B1: Limited

evidence of carcinogenicity from epidemiologic studies; B2: Sufficient evidence

from animal studies; inadequate evidence or no data from epidemiologic studies.

EPA-C: Possible Human Carcinogen: Limited evidence of carcinogenicity in animals

in the absence of human data.