Quantcast Toxicological/Biological Effects - doe-hdbk-1113-98_reaffirm_2005_040118

 

Click here to make tpub.com your Home Page

Page Title: Toxicological/Biological Effects
Back | Up | Next

Click here for thousands of PDF manuals

Google


Web
www.tpub.com

Home

   
Information Categories
.... Administration
Advancement
Aerographer
Automotive
Aviation
Construction
Diving
Draftsman
Engineering
Electronics
Food and Cooking
Logistics
Math
Medical
Music
Nuclear Fundamentals
Photography
Religion
   
   

 

Share on Google+Share on FacebookShare on LinkedInShare on TwitterShare on DiggShare on Stumble Upon
Back
Fire - doe-hdbk-1113-98_reaffirm_2005_040117
Up
Radiological Safety Trainign for Uranium Facilities
Next
Chemical Reactivity - doe-hdbk-1113-98_reaffirm_2005_040119


DOE-HDBK-1113-98
Radiological Safety Training for Uranium Facilities
Module 101 Properties of Uranium
2. Toxicological/Biological Effects
The principal entry of uranium into the human system is due to either inhalation
or ingestion. Inhalation occurs either from release of volatile uranium
compound or from suspension of volatile uranium-laden aerosols. Ingestion can
occur when the uranium is introduced into water for consumption or the food
chain by plant uptake. When uranium is either ingested or inhaled, it is removed
from the body with a biological half-life varying between 6 and 5000 days,
depending on which organ has become contaminated.
Uranium tends to concentrate in the kidneys and the bones. Additionally, if
inhaled, the lungs are exposed. Internal exposure to uranium is controlled by
limiting the ingestion and inhalation of this element. These methods, along with
measurement techniques, are discussed in Module 104.
Most heavy metals, such as uranium, are toxic to humans depending on the
amount introduced into the body. For short-term (acute) exposures, the
toxicological effects are the primary concern, and acute exposures to significant
amounts of uranium may result in kidney damage. However, as the enrichment
of the uranium in the 235U isotope increases, so too do the effects of radiation
exposure in relation to toxicological effects.
Past industrial experience has proven that if there is a long-term exposure of
small amounts of uranium (chronic exposure), the radiological effects are the
primary biological concern. In fact, for chronic exposures, a development of
tolerance against the toxicological effects may occur. The principal radiological
hazard associated with uranium is due to the relatively high energy alpha
particles its radionuclides and daughters emit. A chronic exposure to these
8


Privacy Statement - Press Release - Copyright Information. - Contact Us

Integrated Publishing, Inc.