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Page Title:
Appendix B - Insoluble Metal Tritide Benchmark cont'd |
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|  DOE-HDBK-1184-2004
The lung dissolution rate constants and f1 are defined below. All rate constants are in units of
1/days. Defaults are for type M SMT are: fr=0.1, sr=100, ss=0.005, f1=0.1. For type S:
fr=0.001, sr=100, ss=0.0001, f1=0.01.
fr = 0.1
s r = 100
s s = 0.005
s p = s s + fr⋅(s r - s s)
s pt = (1 - fr)⋅(s r - s s)
st = ss
-1
f1 = 1⋅10
Setting the total removal rate constant for urine to zero defines a zero matrix that has
dimensions of urine x urine (39 x 39 for this model). The individual transfer rate constants
for the respiratory tract are then defined per ICRP 66.
=0
k
urine, urine
= 0.02
= sp
= spt
k
k
k
AI1 , bb1
BB1 , blood
bbseq , Tbbseq
= 0.03
= sp
= spt
k
k
k
bb2 , BB1
BBseq , blood
AI3 , TAI3
= 0.001
= spt
= 100
k
k
k
ETseq , LNet
AI2 , TAI2
ET2, S
= sp
= spt
= spt
k
k
k
AI1 , blood
BB1 , TBB1
LNth, TLNth
= sp
= spt
=2
k
k
k
bb2 , blood
BBseq , TBBseq
bb1 , BB1
= sp
= 0.0001
= sp
k
k
k
ETseq , blood
AI3 , bb1
ET2, blood
= spt
= 0.03
= sp
k
k
k
AI1 , TAI1
BB2 , ET2
LNet , blood
= spt
= 0.01
= sp
k
k
k
bb2 , Tbb2
bbseq , LNth
bb1 , blood
= spt
= 0.00002
= spt
k
k
k
ETseq , TETseq
AI3 , LNth
ET2, TET2
= 0.001
= spt
= sp
k
k
k
AI2 , bb1
LNet , TLNet
BB2 , blood
= 10
= spt
= sp
k
k
k
BB1 , ET2
bb1 , Tbb1
bbseq , blood
= 0.01
=1
= sp
k
k
k
BBseq , LNth
ET1, ENV
AI3 , blood
= sp
= sp
= spt
k
k
k
AI2 , blood
LNth, blood
BB2 , TBB2
The transfer rate constants for the transformed respiratory tract compartments are defined:
=k
=k
=k
k
k
k
TAI1 , Tbb1
AI1 , bb1
TAI2 , Tbb1
AI2 , bb1
TAI3 , Tbb1
AI3 , bb1
=k
=k
=k
k
k
k
TBB2 , TET2
BB2 , ET2
TET2, S
ET2, S
TETseq , TLNet
ETseq , LNet
= st
= st
=k
k
k
k
TAI1 , blood
TAI2 , blood
TAI3 , TLNth
AI3 , LNth
= st
= st
= st
k
k
k
TBB2 , blood
TET2, blood
TETseq , blood
71
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