Ergonomics should be considered in designing the height of glove-box
ports and access to inner surfaces and equipment.
Each glove box should be equipped with an audible alarm that can be
tripped to signal radiological problems. Individuals should be able to
activate the alarm without removing their arms from the glove box. The
alarm should sound in a continuously occupied area where it should, as a
minimum, identify the room in which the alarm originated.
A HEPA filter should be installed on the air inlet to the glove box if
required to prevent the backflow of contamination. Prefilters should be
installed upstream of the HEPA filter where appropriate. The exhaust
outlet for each glove box should have HEPA filters to keep the
ventilation ductwork clean. This filter should not be counted as a formal
HEPA stage and need not meet all the test capabilities for HEPA
filtration; however, it should be tested prior to installation. Push-through
filter change-out systems should be used if possible. The HEPA filters
downstream of the glove box should be readily accessible for filter
change-out and testable.
Glove-box air inlets and inlet filters should be protected or oriented to
prevent inadvertent entry of water into the box (e.g., a fire-sprinkler
system discharge or water-line leak).
Glove boxes should be designed to operate at a negative pressure (0.75 ±
0.25 in. water gage (WG)) with respect to the room in which they are
operated. Differential pressure gauges should be installed on each glove
box or integrally connected series of glove boxes. During abnormal
conditions, control devices to prevent excessive pressure or vacuum
should be either positive-acting or automatic or both. The ventilation
system should be designed to provide and maintain the design negative
pressure during normal operations and the design flow through a breach.
There should be exhaust capacity on demand that will promptly cause an
inflow of air greater than 125 linear ft/min through a breach of at least a
single glove-box penetration of the largest size possible. Filters,
scrubbers, demisters, and other air-cleaning devices should be provided
to reduce the quantities of toxic or noxious gases and airborne
particulates that enter the ventilation system prior to its entry into the
Each glove box or integrally connected series of glove boxes should be
equipped with an audible alarm that alerts personnel when a system
pressure or vacuum loss is occurring. The alarm should be set at -0.5-in.
WG relative to the room in which the glove box is located.
The number of penetrations for glove-box services should be minimized.
The fittings should provide a positive seal to prevent the migration of
radioactive material. For the same reason, penetrations for rotating shafts
should not be permitted except where rotating shafts have seals. Seals for
rotating shafts are very reliable and are preferred to motors inside the