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DOE-STD-1128-98
Guide of Good Practices for Occupational Radiological Protection in Plutonium Facilities
designed and operated to minimize internal exposure. Details regarding workplace monitoring and
control practices are discussed in Section 4.0.
5.1.1 Performance Capabilities for Internal Exposure Monitoring
Bioassay monitoring programs must be capable of showing compliance with the 5-rem/year
stochastic and 50-rem/year nonstochastic dose limits of 10 CFR 835.202 (DOE, 1998a).
10 CFR 835.402(c)(1) (DOE, 1998a) identifies 100-mrem CEDE and/or 5 rem CDE to any
organ or tissue for all likely intakes as a level above which workers must participate in a
bioassay program. Therefore, ideally, such bioassay monitoring programs should be capable
of detecting those levels. In fact, this is not technically achievable for most routine
plutonium bioassay programs. In order to meet this requirement, reliance must be placed on
workplace monitoring to identify potential intakes at the time they occur so that special
bioassay monitoring can be initiated. Routine, periodic bioassay measurements have little
chance of detecting a CEDE of 0.1 rem and can even have difficulty showing compliance
with dose limits.
Performance capabilities for bioassay and internal dosimetry programs can be expressed as
the minimum detectable dose, based on some combination of minimum detectable activity
and frequency of measurement or time post-intake at which the measurement is made. The
term "minimum detectable dose" is preferred over any variants of the occasionally
encountered terms "dose-missed" or "potentially undetected dose," which were usually
defined as the same thing. The connotation of the latter terms is that of an actual intake
which was not detected, whereas the intent was to define a measure of program sensitivity to
doses that might have gone undetected had an intake occurred. The preferred term
"minimum detectable dose" (MDD) ties the concept to the recognized terminology of
minimum detectable activity (MDA).
The MDD for a bioassay monitoring program must meet the aforementioned dose limit
requirements of 10 CFR 835.202. A design goal of 100-mrem CEDE from all intakes of
similar nuclides in a year is desirable but unrealistic for a routine program. To meet these
requirements, bioassay programs should have measurement sensitivities (i.e., MDAs for
bioassay measurements) established based on the material to which workers might be
exposed. Examples of such sensitivities are given in Tables 5.1 and 5.2 for pure 239Pu
monitored by urinalysis and fecal analysis, respectively. Table 5.3 provides an example of
the 241Am sensitivity required for monitoring a mixture of weapons-grade plutonium, aged
5 years for ingrowth at time of intake. These tables illustrate the difficulty in relying on
routine bioassay to demonstrate compliance with the limits and design goal.
5-3


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