Methods of Minimizing Cross Contamination - doe-hdbk-1106-97

DOE-HDBK-1106-97

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Methods of Minimizing Cross Contamination

Cross contamination may cause the radioactive materials used in one experiment to turn

up unexpectedly in the results of another. Since some experiments utilize only minute

amounts of radinuclides while others use large amounts, it is easy to visualize the

confusion when large amounts of unknown radionuclides appear suddenly in a low-level

experiment.

Cross contamination can result from mishandling; contaminated protective clothing;

contaminated cages, food, and water supplies; and airborne materials being transferred

from cage to cage.

Contaminated cages should be allowed to decay where possible, and then be thoroughly

washed. Following washing, they must be surveyed before re-use.

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Room Contamination Problems

These problems can best be avoided by maintaining radioactive animals in a separate

room and maintaining high standards of housekeeping in the room. Feces, cage linings,

and urine should be stored in the appropriate containers. These items should not be

allowed to accumulate.

In case any of the above-mentioned items are spilled, they should be cleaned up

immediately, utilizing absorbent, disposable materials. All materials used in cleaning up a

spill should be placed in the appropriate containers to preclude the possibility of further

contamination spread. It is essential that spills be cleaned up without delay.