Requirements for Laboratory Use of Chemicals

DOE-HDBK-1139/3-2005

Sources11

Consolidated Requirements12

4.3

Requirements for Laboratory Use of Chemicals

4.3.1

A chemical hygiene plan shall be prepared for laboratory

29CFR1910.1450(e)(3)

operations that includes safe operating procedures, hazard

control measures, operability requirements for protective

equipment, provisions for employee training and medical

consultations, designation of individuals responsible for

implementing the plan, and provisions for employee

protection against extremely hazardous substances.

4.3.1.1 Particularly hazardous substances include "select

29CFR1910.1450(e)(3)(viii)

carcinogens," reproductive toxins, and substances

with a degree of acute toxicity. Provisions, where

appropriate, shall include:

Establishment of a designated area for storage

Use of containment devices

Procedures for safe removal of contaminated

waste

Decontamination procedures

4.3.2

Fire Hazard Classification Laboratory units shall be

NFPA 45, 2.2.1.1-4

classified Class A (High Fire Hazard), Class B (Moderate

fire Hazard), Class C (Low fire Hazard), or Class D

(Minimal Fire Hazard), according to the quantities of

flammable and combustible liquids present in the lab

(outside of the storage area) as specified in Table 2.2.1(a)

and Table 2.2.1(b) in NFPA 45.

4.3.2.1 For the purposes of determining laboratory fire hazard

NFPA 45, 2.2.1.5

classification and the use of tables 2.2.1(a) and (b),,

quantities of liquefied flammable gases shall be

treated as if they were Class I flammable liquids (see

definition); that is, 4L (1.1gal) of liquefied flammable

gas is to be considered equivalent to 4L (1.1 gal) of

Class I flammable liquid.

4.3.3 All laboratory units shall be provided with fire protection

NFPA 45, 4.1-4.6

appropriate to the fire hazard, including: automatic fire

extinguishing systems, standpipe and hose systems,

portable fire extinguishers, fire alarm systems, fire

prevention programs, and emergency plans.