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| DOE-HDBK-1184-2004
The first step in calculating He is to calculate the individual organ doses. To do this
we must know:
The source organs8;
The number of decays that take place in the source organs;
The target organs 9; and
The fraction of energy released in the source organs that is absorbed in a target
organ.
The source organs for STC are listed in Table 5-4.
Table 5-4. Dosimetric source organs for intakes of STC.
ET1sur bbseq
ET2sur
AI
ET2seq LNth
LNet
UBcont
BBgel
SI
BBsol
ULI
BBseq
LLI
bbsol
tissue
bbgel
The abbreviation "sur" refers to surface, "seq" refers to sequestered, "gel" refers to
material in the fast clearing mucus on top of the cilia, and "sol" refers to material in
the slow clearing solution between cilia. The source organ "tissue" is the soft
tissues of the body.
A source organ may be associated with more than one biokinetic compartment. For
example, the source organ ET1sur is composed of only the ET1 biokinetic
compartment, whereas the ET2sur source organ is composed of the ET2 and
transformed ET2 (TET2) biokinetic compartments. The "tissue" source organ is
composed of the OBT, HTO, and blood biokinetic compartments (see Appendix B).
The decays U that take place in the source organs are calculated by integrating the
retention function for the biokinetic compartments that compose the source organ.
Once the source organs and their associated biokinetic compartments are
specified, the target organs must be specified. The target organs for STC are listed
in Table 5-5.
8
The organs in which tritium will decay and release radiation.
9
The organs that absorb the radiation emitted by the source organs.
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