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  | ![]() DOE-HDBK-1130-98 
Module 2: Biological Effects 
Instructor's Notes 
I. 
MODULE INTRODUCTION 
A. 
Self Introduction 
1. Name 
2. Phone Number 
3. Background 
B. Module Overview 
The fact that ionizing radiation produces biological damage 
has been known for many years. We have gained most of 
our knowledge of these effects since World War II. 
In this module, we will discuss the potential for biological 
effects and risks due to ionizing radiation and put these 
potential risks into perspective when compared to other 
occupations and daily activities. With this information, it is 
hoped that employees will develop a healthy respect for 
radiation rather than fear or disregard. 
C. Objectives Review 
D. Introduction 
We know more about the biological effects of ionizing 
radiation than most other environmental factors. Rather than 
just being able to base our information on animal studies, we 
have a large body of information available regarding 
exposures to humans. There are four major groups of people 
that have been exposed to significant levels of radiation. 
The first group includes early radiation workers, such as 
radiologists. These workers received large doses of radiation 
before the biological effects were recognized. Since that time, 
standards have been developed to protect workers. 
The second group is the more than 250,000 survivors of the 
atomic bombs dropped at Hiroshima and Nagasaki. Some of 
these survivors received doses estimated to be in excess of 
50,000 mrem. 
The third group includes individuals who have been involved 
in radiation accidents. 
The fourth and largest group of individuals are patients who 
have undergone radiation therapy for cancer and other 
diseases. 
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