Table XIII. Early Bioassay Measurement Results Corresponding to the Therapeutic Intervention Action Levels Used at the Hanford Site (Carbaugh et al. 1995) (Part 2)

DOE-STD-1121-98

Table XIII. Early Bioassay Measurement Results Corresponding to the Therapeutic Intervention

Action Levels Used at the Hanford Site (Carbaugh et al. 1995) (Part 2)

Measurement

Result

Action

Possible

Isotope and

Dose (HE,50)

Treatment

Uranium, Soluble

Potential

Chest count

>MDA (14-21 mg)

Consider

Na or Ca

kidney

therapy

bicarbonate;

toxicity

Second-void

>0.1 mg

intestinal

urine sample

adsorbents

12-hour urine

>0.5 mg

sample

Uranium Insoluble(a)

>MDA for 235U or

Consider

None

2 rems

Chest count

234

therapy

recommended

200 rems

Same

100 x ALI

Treatment

Lung lavage

strongly

recommended

Plutonium or 241Am

2 rems

Chest count

>MDA for Pu or

241

Consider

DTPA

Early urine

>4 dpm when

therapy

sample

extrapolated to first

day excretion

(a)

If soluble component is present, then urine sampling is appropriate.

Use same action levels as above for soluble uranium.

skin integrity will not be breached. Therapeutic actions to reduce internal dose once an intake has

occurred will likely require administration under the direction of competent medical authority.

Skin decontamination can generally be accomplished by simple washing with mild soap and water.

If contamination persists, an abrasive pumice soap, detergents, and commercial decontamination agents

containing complexing agents such as EDTA (ethylenediaminetetra-acetic acid) may be effective. A final

step in skin decontamination is the use of a saturated solution of potassium permanganate which is

painted onto the skin with an applicator or cotton ball, followed by removal using a sodium bisulfite

solution. The potassium permanganate/ sodium bisulfite procedure removes a thin layer of dead skin.

Repeated applications of this method are cautioned because its overuse can result in epidermal irritation

or burning, with possible loss of skin integrity and subsequent uptake. An extreme example of

decontamination is the surgical debridement (aggressive cleaning) or excision (cutting out) of

contaminated material from a wound. Details on skin decontamination methods can be found in NCRP

108