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DOE-SPEC-1142-2001
B.2.
For each Treatment Group calculate the median of the Ln counts (see Table B-II
column 6).
Table B-II
Treatment Group
Ln (well counts)
Median
Day5 controls
7.1066
7.7795
7.4810
6.8533
7.2819
Day5 controls
7.3126
7.3576
7.2513
7.0309
7.2819
Day5 controls
6.8763
7.7253
7.4634
6.5903
7.2819
Day5 Be1
7.4827
7.5443
7.4396
7.5417
7.5122
Day5 Be10
8.1221
8.8847
7.2951
8.0382
8.0801
Day5 Be100
8.1973
8.2039
7.8047
7.3988
8.0010
Day7 controls
8.1931
9.7648
8.2913
8.0533
8.0123
Day7 controls
6.5058
7.1365
7.3112
8.4029
8.0123
Day7 controls
7.9714
8.3366
7.2196
7.0493
8.0123
Day7 Be1
7.4206
7.6898
6.4441
7.1420
7.2813
Day7 Be10
5.7991
6.3936
5.5373
5.5759
5.6875
Day7 Be100
8.1917
8.3975
9.5786
9.6086
8.9880
PHA
11.534
10.697
10.991
10.841
10.916
CONA
11.658
11.553
12.438
11.979
11.819
B.3 For each beryllium concentration, calculate the Ln(SI) by subtracting the median of the
control wells from the median of the Be stimulated wells, e.g., for Day5 Be100 the
Ln(SI) = 8.0010 - 7.2819 = 0.7191 and the SI is exp(0.7191) = 2.05.
B.4 Calculate the standard deviation of the Ln counts (corresponds to CV on original scale). In
EHP96 this is referred to as "phitilde". The median absolute deviation (MAD) estimate
given on page 960 (called here Sm--- the MAD estimate of the standard deviation), is
Sm = 1.48 * median[ absolute(residual) ] * √[n/(n-p)] where:
absolute(residual) = the absolute value of the (Ln well count - the median Ln well count);
n the number of data values is 24, if 12 control wells and 12 exposed wells; and
p the number of parameters is 4, if 1 median for control wells and 3 medians for exposed
wells.
A separate estimate of Sm is calculated for Day 5 and Day 7, since it has been observed that
there is generally more variability on Day 7. Using Day 5 as an example, the residuals are
listed in Table B-III.
14


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