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  | ![]() DOE-HDBK-1130-98 
Module 2 Biological Effects 
Instructor's Notes 
1. Acute radiation doses 
a. High doses of radiation received in a short period of time 
EO5 Define the terms "acute 
are called acute doses. The body's cell repair 
dose" and "chronic dose." 
mechanisms are not as effective for damage caused by an 
acute dose. 
b. 
Acute doses to the whole body 
After an acute dose, damaged cells will be replaced by 
new cells and the body will repair itself, although this 
may take a number of months. Only in extreme cases, 
such as with the Chernobyl firefighters (500 rem), would 
the dose be so high as to make recovery unlikely. 
c. 
Acute doses to only part of the body 
1) X-ray machines 
It is possible that radiation exposure may be limited to a 
part of the body, such as the hands. 
There have been accidents, particularly with X-ray 
machines, in which individuals have exposed their 
fingers to part of the intense radiation beam. In some of 
these cases, individuals have received doses of millions 
of mrem to their fingers, and some individuals have lost 
their finger or fingers. It is important for individuals 
who work with X-ray or similar equipment to be trained 
in the safe use of this equipment. 
Reference 5. 
2) Radiation therapy 
a) Radiation therapy patients receive high doses of 
radiation in a short period of time, but generally only to a 
small portion of the body (not a whole body dose). 
b) The skin and limited tissue of these patients may receive 
significant doses, but doses to the region of a tumor are 
many times higher. 
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