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  | ![]() DOE-HDBK-1130-98 
Module 2 Biological Effects 
Instructor's Notes 
c) Ionizing radiation is used to treat cancer in these patients 
because cancer cells are rapidly dividing and therefore 
sensitive to ionizing radiation. Some of the side effects 
of people undergoing radiation therapy are hair loss, 
nausea, and tiredness. 
d. Probability of a large acute dose 
What is important to understand is that it takes a large 
acute dose of radiation before any physical effect is seen. 
These acute doses have occurred in Hiroshima/Nagasaki, 
and in a few radiation accidents, including Chernobyl. 
The possibility of a radiological worker receiving a large 
acute dose of ionizing radiation on the job is extremely 
low. Typically, radioactive materials are handled in 
small quantities that do not produce a large amount of 
radiation. Where there is a potential for larger 
exposures, many safety features are required. 
2. 
Chronic radiation doses 
EO5 Define the terms "acute 
A chronic radiation dose is typically a small amount of 
dose" and "chronic dose." 
radiation received over a long period of time. An 
example of a chronic dose is the dose we receive from 
natural background every day of our lives. The body's 
EO6 State examples of 
cell repair mechanisms are better able to repair a 
chronic radiation dose. 
chronic dose than an acute dose. 
a. 
The body has time to repair damage because a smaller 
percentage of the cells need repair at any given time. 
b. 
The body also has time to replace dead or non- 
functioning cells with new, healthy cells. 
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