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  | ![]() DOE-HDBK-1130-98 
Module 2 Biological Effects 
Instructor's Notes 
3. Biological effects of radiation exposure 
Somatic effects refer to the effects radiation has on the 
individual receiving the dose. 
EO7 Define the term 
Genetic effects refer to mutations due to radiation 
"heritable effect." 
damage to the DNA of a cell. When this change is in the 
DNA of parental reproductive cells, it is called a 
heritable effect. 
a. Somatic Effects 
Somatic effects can best be described in terms of prompt 
and delayed effects as discussed below. 
3) Prompt Effects 
Although rare in the nuclear industry, large doses are 
typically acute radiation doses representing serious 
overexposures. The biological effects of large acute 
doses are as follows: 
Table 2-1 
Prompt Biological Effects 
Dose (rem) 
Effect 
0-25 
None detectable through 
symptoms or routine blood 
tests. 
25-100 
Changes in blood. 
100-300 
Nausea, anorexia. 
300-600 
Diarrhea, hemorrhage, and 
Effects are dependent on 
medical intervention and the 
possible death 
individual. 
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