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|  DOE-HDBK-1106-97
Radiological Contamination Control Training
for Laboratory Research
Student's Guide
IODINE-125 (I-125)
Iodine-125 is a gamma and X-ray emitter. I-125 contamination may be detected by a thin-window G-M
probe or with liquid scintillation counting.
1.
Maximum energy: 0.035 MeV gamma (6.5%), 0.027 MeV x-ray (112.5%) and 0.031 MeV
X-ray (25.4%).
IAEA toxicity classification: Medium-high.
2.
Physical half-life: 60 days.
3.
Effective half-life (Teff): 42 days.
4.
Critical organ: Thyroid gland.
5.
Personnel monitoring: Internal uptakes evaluated by thyroid scan.
6.
ALI:
7.
0.06 mCi (2 x 106 Bq) by inhalation, daily clearance.
o
0.04 mCi (1 x 106 Bq) by ingestion.
o
Shielding: 0.25 mm of lead is the first half-value layer.
8.
9.
Other considerations for iodine compounds:
o
Volatilization of iodine (NaI) is the most significant hazard.
o
Simply opening a vial of sodium iodide at high-radioactive concentrations can cause
minute droplets to become airborne.
o
Solutions containing iodide ions should not be made acidic nor stored frozen; both lead
to formation of volatile elemental iodine.
o
Some iodide compounds can penetrate surgical rubber gloves - wear two pairs or
polyethylene gloves over rubber.
o
Can be easily absorbed through the skin.
A-19
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