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DOE-STD-1066-99
15.3.3 Multiple Hazard Gloveboxes
If a glovebox operation involves multiple hazards (such as pyrophoric metal and
flammable/combustible liquids), the FHA should determine the fire protection system
design that provides the best overall protection.
15.3.4 Special Hazards
Gloveboxes in which other special hazards are present (such as biohazards, medical
or industrial toxins, flammable solids, water reactive materials, etc.) should be
equipped with fire protection as determined by the FHA.  At a minimum, this
protection should consist of an automatic fire detection system complying with NFPA
Standard 72 and the guidelines in Section 15.5 of this standard.
15.3.5 Gloveboxes Removed from Service
15.3.5.1
Fire suppression and inerting systems are not required to be maintained
in gloveboxes which are removed from service provided that the following
provisions are met:
o All combustible materials are removed from the glovebox.
o Electrical power and flammable/combustible utilities are isolated and
tagged "out-of-service."
o The glovebox is tagged "out-of-service."
15.3.5.2 Resumption of activities within the glovebox should only be allowed after
appropriate fire protection features have been reactivated on the basis of an
updated FHA.
15.4 Manual Fire Suppression
15.4.1 Manual Fire Fighting
15.4.1.1 All glovebox designs should include provisions for manual fire fighting. The
extinguishing agent(s) selected should be appropriate for the hazards.
15.4.1.2 Where the potential for metal fires is present, an appropriate fire
extinguishing agent (e.g., magnesium oxide sand, copper metal powder (30
- 60 mesh), carbon microspheres) in sufficient quantity should be provided.
(Refer to Appendix G for an illustration of a mounting concept for a dry
powder container.) In selecting the fire extinguishing agent, consideration
should be given to the ease at which the metal can be separated from the
agent. This is particularly relevant in the case of plutonium.
15.4.1.3 Where the fire potential is from other (non-metal) combustibles, dry chemical
extinguishers are recommended. CO2 extinguishers may also be considered
if class A combustibles are not a hazard in the glovebox. If grouped cables
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